The toxification theory of aging suggests that the accumulation of toxins and the body's decreased ability to eliminate them contribute to the aging process. Toxins can come from various sources, including environmental pollutants, dietary factors, and metabolic byproducts. Over time, the accumulation of toxins can lead to cellular damage and dysfunction, contributing to aging and age-related diseases. Detoxification processes, such as liver function and antioxidant defense mechanisms, become less efficient with age, further exacerbating the toxic burden on the body.