The DNA methylation theory of aging focuses on epigenetic changes that occur with age. Epigenetics refers to modifications to the DNA molecule that can influence gene expression without altering the underlying DNA sequence. DNA methylation, one such epigenetic modification, involves the addition of a methyl group to DNA, which can affect gene activity. With age, DNA methylation patterns can change, leading to altered gene expression and potentially impacting various cellular processes. These changes in DNA methylation have been associated with age-related diseases and the aging process itself. Understanding and potentially modifying DNA methylation patterns may offer insights into interventions to promote healthy aging.